BREAST IMPLANTS ARE THE ENHANCEMENT OF THE IMMUNE SYSTEM

SCLERODERMA/"clustering" of autoimmunity besides lupus and myeloma.

I feel that not alot with the exposure to breast implants will get myeloma only those with the genetic predispostion, BUT BREAST IMPLANTS WILL INDEED ENHANCE THE IMMUNE RESPONSE as we are ALL dealing with the total ENHANCEMENT of ones immune response whether end result is "classic autoimmunity" or "not classic autoimmunity". I do see this as we are living it as my maternal grandmother who had very, very bad RA/"clustering" of autoimmunity died from myeloma. My mother died from myeloma June1994. They both were smokers, took "hits" of a different trigger smoking:

Aflatoxin/aspergillus flavus, Tobacco, Ammonia, The p-53 Tumor Suppressor Gene, which is cancer's missing link. My children and I were exposed to breast implants. These children took "hits" via the placental barrier through fetal cells in autoimmunity. Breast feeding was extra "hits". I have MS, asthma, a poorly defined CTD, problems in the spine at L4-L5 and more. Our daughters have health concerns. Our 10 yr old has scleroderma (scleroderma runs hand-in-hand with silica exposure), a swallowing disorder and an "acral bone dysplasia" (silica binds the bone). I will go further as I question MICROCHIMERISM/GVHD~FETAL CELLS IN AUTOIMMUNITY. Microchimerism which refers to "the presence of foreign cells in one's body.

So put microchimerism which is the presence of foreign cells in one's body along with taking "hits" of foreign protein excesses (silicone in this case) along with a genetic predisposition/"clustering" of autoimmunity and a POSSIBLE "TWO HIT" THEORY...Then how many "hits" does it take to cross the threshold to the chronic/defined disease? "Two hits", "five hits", "ten hits" or more? AND what about HERVs, ALU and jumping genes in this whole process? END RESULT, I feel will indeed be the enhancement of the immune system, plain and simple! CAUSATION OF SILICONE is the ENHANCEMENT OF THE IMMUNE RESPONSE! AND different triggers will produce different symptoms, sometime UNIQUE symptoms. Living this 24/7 in my own family.

These researchers from Harvard as others need to look at the big picture of the ENHANCEMENT OF THE IMMUNE RESPONSE. Which is the immune system only going through the proper changes given the environmental trigger/time factor of exposure which is ENHANCING the immune system totally. Because the enhancement the immune system goes out of control as it was programmed in a different way, seeing what it was exposed to, in this case silicone breast implants! Researchers care to see what they wish to see...and the medical mind should not/CAN NOT be made up once and for all that breast implants are "safe" and have an "acceptable risk".

Subject: [MMA] No Link Seen Between

Date: Sat, 31 Mar 2001 14:14:08 -0800

Multiple Myeloma Association (MMA) -

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No Link Seen Between

MGUS and Breast Implants

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BOSTON--The purported association between breast implants and monoclonal gammopathy of undetermined significance seems to be fading.

A Harvard team reported that the rate of MGUS was comparable among 288 women who'd had or still had breast implants and 288 women who'd never had implants-five vs. Four patients.

It was the sixth study, though the first cohort study using stored blood samples instead of medical records, to find no association. In contrast, three case series and the National Cancer Institute's registry, all reported in 1996, reported an association.

The nine with MGUS came from the 32,826 women in the prospective Nurses' Health Study who provided 30 ml of blood in 1988 for future research. None of the nine had developed multiple myeloma or other hematologic disease by 1996, reported rheumatologist Elizabeth W. Karlson of Brigham and Women's and olleagues in the March 26 Archives of Internal Medicine. Eventually 24% of women with MGUS develop multiple myeloma, macroglobulinemia, amyloidosis, or related diseases.

Among the five women with implants who developed MGUS, three had devices filled with silicone gel, though a separate analysis showed no significant association between this kind of device and MGUS. One woman had a saline implant and the other was unknown.

The five women averaged eight years older than the four in the control group with MGUS. The investigstors said this indicated that implants do not cause MGUS at a younger than expected age. Other reports found multiple myeloma developing at unusually young ages among women with silicone breast implants.